Sanchez has three goals and three assists in five lifetime matches against Watford, while Ozil has a goal and three assists in five contests.
Silva will openly acknowledge that his team are up against it against Arsenal, but his players will not be lacking belief against opposition who are missing a key defender and have a number of players potentially returning to make their first appearance in a number of weeks.
"Yes, I have. I think about sorting out the problem, but overall I will completely decide what I do tomorrow because Koscielny will have a test then", Wenger said.
Alexandre Lacazette to continue his fine goal scoring run and claim the first goal is 15/4.
Arsenal have won three of the last four editions of the FA Cup, but Watford are the only team to have beaten Arsenal in the competition since 2014. Nacho Monreal and Alex Iwobi were both on target for the Gunners.
Sanchez, too, also remains in Wenger's plans but the Chilean has netted just once this season and this game comes just days after Chile failed to qualify for the 2018 World Cup.
And following reports that Wilshere could leave Arsenal in January to earn a spot in England's World Cup squad, Wenger claimed the 25-year-old would not have to leave the Emirates in order to make Gareth Southgate's squad for Russian Federation.
Arsenal are strong favourites to win this game with the bookies, at 3/5.
LONDON, ENGLAND - SEPTEMBER 14: Hector Bellerin of Arsenal celebrates his side's victory following the UEFA Europa League group H match between Arsenal FC and 1.
Watford have been excellent this season, but they are perhaps facing Arsenal at the wrong time. We are getting a really good price on this bet and as a result, I think we should take it.